Splice

Plot

Elsa and Clive, two rebellious young scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators — only to have that bond turn deadly.

Cast

Adrien Brody

Clive Nicoli

Sarah Polley

Elsa Kast

Delphine Chanéac

Dren

Brandon McGibbon

Gavin Nicoli

Simona Măicănescu

Joan Chorot

David Hewlett

William Barlow

Abigail Chu

Child Dren

Doug Hicton

Lab tech (uncredited)